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Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium

21 Mar 2025

Abstract excerpt

Gastrointestinal colonization by the nosocomial pathogen vancomycin-resistant Enterococcus faecium (VREfm) can lead to bloodstream infections with high mortality rates. Shifts in VREfm lineages found within healthcare settings occur, but reasons underlying these changes are not understood. Here we sequenced 710 VREfm clinical isolates collected between 2017 and 2022 from a large tertiary care centre. Genomic...

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PMID: 40119148
DOI: 10.1038/s41564-025-01958-0

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