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Article

Reflections Regarding Validation of New HPV Tests With Reduced HPV Genotypes: Report From an IARC Expert Consultation.

Journal of medical virology - 1 Mar 2025

Ramírez Arianis Tatiana, Clifford Gary M, Dillner Joakim, Kuhn Louise, Arbyn Marc, Bhatla Neerja, Wentzensen Nicolas, Sasieni Peter, Abraham Priya, Rol Mary Luz, Almonte Maribel, Basu Partha

Abstract excerpt

Of the 12 HPV genotypes classified as carcinogenic to humans (Group 1), over 95% of HPV-positive cervical cancers are linked to eight genotypes (HPV16/18/31/33/35/45/52/58). Screening programmes may consider HPV tests incorporating only these genotypes to improve screening efficiency and reduce programmatic costs. Validation of such tests requires fine-tuning of existing criteria. An expert group convened by the...

Read the complete abstract on PubMed

Topics

Humans
Papillomavirus Infections
Female
Genotype
Uterine Cervical Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Early Detection of Cancer

Papillomaviridae

Sensitivity and Specificity

Genotyping Techniques

Source

Identifiers

PMID: 40109087
DOI: 10.1002/jmv.70310

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