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Article

Vitamin D receptor FokI polymorphism as a risk factor for painful diabetic neuropathy in type 2 diabetes mellitus patients.

Journal of neurogenetics - 1 Mar 2025

Vania Aurelia, Samatra Dewa Putu Gde Purwa, Adnyana I Made Oka, Saraswati Made Ratna, Darwinata Agus Eka, Widyadharma I Putu Eka

Abstract excerpt

Painful diabetic neuropathy (PDN) is a common complication in patients with type 2 diabetes mellitus (T2DM) with disruption of vitamin D (VD) activity as one of the risk factors. Active VD exerts its biological functions through the vitamin D receptor (VDR), which polymorphisms in the VDR gene can impair. This study aims to establish VDR FokI and ApaI polymorphisms as risk factors for PDN. This case-control study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40071652
DOI: 10.1080/01677063.2025.2473705

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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