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Molecular epidemiology and β-lactam resistance mechanisms of Enterobacter cloacae complex isolates obtained from bloodstream infections, Kyoto, Japan.

Microbiology spectrum - 1 Apr 2025

Matsuo Akihiko, Matsumura Yasufumi, Mori Keiichiro, Noguchi Taro, Yamamoto Masaki, Nagao Miki

Abstract excerpt

The Enterobacter cloacae complex (ECC) comprises multiple species that require genomic analysis for precise identification. They produce inducible AmpC β-lactamase and may carry acquired β-lactamases, which are responsible for cefotaxime and cefepime resistance. To determine the molecular epidemiology, antimicrobial resistance, and β-lactam resistance mechanisms of the ECC, we conducted whole-genome sequencing...

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PMID: 40062888
DOI: 10.1128/spectrum.02485-24
PMCID: PMC11960451

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