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Resistome and virulome determination in Helicobacter pylori using next-generation sequencing with target-enrichment technology

5 Mar 2025

Abstract excerpt

ABSTRACT The identification of Helicobacter pylori infection from gastric biopsy samples requires PCR or bacterial cultures. However, it is difficult to culture H. pylori because it is a fragile bacterium. Next-generation sequencing (NGS) allows direct assessment of the resistome and virulome. Here we describe a new NGS method for studying the resistome and virulome of H. pylori directly from gastric biopsies,...

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PMID: 40042287
DOI: 10.1128/spectrum.03298-24

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