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ALKBH1 knockdown promotes the growth, migration and invasion of HTR-8/SVneo cells through regulating the m5C modification PSMD14

1 Mar 2025

Abstract excerpt

Preeclampsia (PE) is a pregnancy disease characterized by insufficient invasion and growth of trophoblast cells. adeno-associated virus encoding alkB homolog 1 (ALKBH1) is a demethylase in 5-methylcytosine (m5C) methylation modification. This study was performed to explore the role of ALKBH1 in hypoxia treated human extravasated trophoblast cells. Hypoxia treated human extravasated trophoblast cells (HTR-8/SVneo)...

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Share to Epigenetics and DNA Methylation
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PMID: 40025166
DOI: 10.1038/s41598-025-91233-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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