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Article

Predisposing conditions in patients with small intestinal adenocarcinomas in the Netherlands: A 20-year nationwide cohort study.

International journal of cancer - 15 Jul 2025

Linssen Jasmijn D G, Schafrat Pascale J M, de Back Tim R, van Erning Felice N, van Leerdam Monique E, Dekker Evelien, Vermeulen Louis, de Hingh Ignace H J T, Sommeijer Dirkje W

Abstract excerpt

Small intestinal adenocarcinomas (SIAs) are associated with predisposing conditions, including inflammatory bowel disease (IBD) and celiac disease, but also genetic syndromes such as Lynch syndrome (LS) and familial adenomatous polyposis (FAP). This nationwide cohort study investigated the incidence of genetic and non-genetic predisposing conditions in SIA and their influence on tumor characteristics and clinical...

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Identifiers

PMID: 39907526
DOI: 10.1002/ijc.35354
PMCID: PMC12079630

Genes

FAP

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