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PRRSV-2 variant classification: a dynamic nomenclature for enhanced monitoring and surveillance.

mSphere - 25 Feb 2025

VanderWaal Kimberly, Pamornchainavakul Nakarin, Kikuti Mariana, Zhang Jianqiang, Zeller Michael, Trevisan Giovani, Rossow Stephanie, Schwartz Mark, Linhares Daniel C L, Holtkamp Derald J, da Silva João Paulo Herrera, Corzo Cesar A, Baker Julia P, Anderson Tavis K, Makau Dennis N, Paploski Igor A D

Abstract excerpt

Existing genetic classification systems for porcine reproductive and respiratory syndrome virus type 2 (PRRSV-2), such as restriction fragment length polymorphisms and sub-lineages, are unreliable indicators of close genetic relatedness or lack sufficient resolution for epidemiological monitoring routinely conducted by veterinarians. Here, we outline a fine-scale classification system for PRRSV-2 genetic variants...

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PMID: 39846734
DOI: 10.1128/msphere.00709-24
PMCID: PMC11852939

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