Maternal exposure to deltamethrin during pregnancy and lactation impairs hippocampal learning and memory function of male offspring by ferroptosis

Abstract excerpt

Deltamethrin (DM), a broad-spectrum insecticide, is widely used in the world. It can exert direct action on the central nervous system to produce neurotoxicity. Exposure to DM can lead to iron metabolism disorder, oxidative stress and learning and memory dysfunction. In our study, pregnant Wistar rats were randomly divided into four groups and gavaged at doses of 0, 1, 4 or 10 mg/kg/d DM from gestational day (GD)...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Epigenetics and DNA Methylation
• Share to Ferroptosis and cancer prognosis
• Share to MicroRNA in disease regulation