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Ongoing measles outbreak in Romania: Clinical investigation and molecular epidemiology performed on whole genome sequences.

PloS one - 1 Jan 2025

Hohan Robert, Surleac Marius, Miron Victor Daniel, Tudor Andreea, Tudor Ana-Maria, Săndulescu Oana, Vlaicu Ovidiu, Aramă Victoria, Pițigoi Daniela, Hristea Adriana, Drăgănescu Anca Cristina, Paraskevis Dimitrios, Bănică Leontina, Oțelea Dan, Paraschiv Simona

Abstract excerpt

AIM: Romania is currently facing a prolonged measles outbreak. The aim of the study was to analyse the circulating human measles virus (HMV) strains by combining whole genome sequencing (WGS) with phylogenetic analysis, with a focus on the haemagglutinin gene. METHODS: We conducted an observational study in the first five months of 2024, in which 168 patients diagnosed with measles were randomly included. We have...

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PMID: 39813269
DOI: 10.1371/journal.pone.0317045
PMCID: PMC11734985

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