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Salivary proteomics and metaproteomics identifies distinct molecular and taxonomic signatures of type-2 diabetes

10 Jan 2025

Abstract excerpt

BACKGROUND: Saliva is a protein-rich body fluid for noninvasive discovery of biomolecules, containing both human and microbial components, associated with various chronic diseases. Type-2 diabetes (T2D) imposes a significant health and socio-economic burden. Prior research on T2D salivary microbiome utilized methods such as metagenomics, metatranscriptomics, 16S rRNA sequencing, and low-throughput proteomics....

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PMID: 39794871
DOI: 10.1186/s40168-024-01997-5

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