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Article

Association Among MCT1 rs1049434 Polymorphism, Athlete Status, and Physiological Parameters in Japanese Long-Distance Runners.

Genes - 19 Dec 2024

Seki Shotaro, Kobayashi Tetsuro, Beppu Kenji, Nojo Manabu, Hoshina Kosaku, Kikuchi Naoki, Okamoto Takanobu, Nakazato Koichi, Hwang Inkwan

Abstract excerpt

BACKGROUND/OBJECTIVES: Monocarboxylate transporters (MCTs) comprise 14 known isoforms, with MCT1 being particularly important for lactate transport. Variations in lactate metabolism capacity and aerobic performance are associated with the T1470A polymorphism in MCT1. We aimed to investigate the frequency of the T1470A polymorphism and compare relevant physiological parameters among long-distance runners, wherein...

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PMID: 39766893
DOI: 10.3390/genes15121627
PMCID: PMC11675177

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