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Genetic and Phenotypic Intra-Clade Variation in Candida auris Isolated from Critically Ill Patients in a New York City Tertiary Care Center.

Clinical chemistry - 3 Jan 2025

Smithgall Marie C, Kilic Abdullah, Weidmann Maxwell, Ofori Kenneth, Gu Yue, Koganti Lahari, Mi Shijun, Xia Hongai, Shi Jun, Pang Jiuhong, Mansukhani Mahesh, Hsiao Susan, Wu Fann

Abstract excerpt

BACKGROUND: Candida auris is an emerging multidrug-resistant pathogen. Interpretation of susceptibility testing can be difficult since minimum inhibitory concentration (MIC) breakpoints have not been fully established. METHODS: All C. auris isolates from unique patients identified at a large urban hospital between 2020 and 2024 (n = 66) underwent whole-genome sequencing (WGS). Genomic DNA was extracted from pure...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39749502
DOI: 10.1093/clinchem/hvae185

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