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Spatiotemporal dynamics of early oogenesis in pigs

2 Jan 2025

Abstract excerpt

BACKGROUND: In humans and other mammals, the process of oogenesis initiates asynchronously in specific ovarian regions, leading to the localization of dormant and growing follicles in the cortex and medulla, respectively; however, the current understanding of this process remains insufficient. RESULTS: Here, we integrate single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) to comprehend...

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PMID: 39748324
DOI: 10.1186/s13059-024-03464-8

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