Article
Validation of a simplified HPV genotyping assay designed for cervical screening in low-resource settings.
Journal of clinical microbiology - 19 Feb 2025
Desai Kanan T, Ajenifuja Kayode O, Adepiti Clement A, Inturrisi Federica, Dagnall Casey, Hoffman Amanda C, Egemen Didem, Gage Julia C, Wentzensen Nicolas, de Sanjose Silvia, Schiffman Mark
Abstract excerpt
Human papillomavirus (HPV) genotype predicts cervical cancer risk, and genotyping could help guide the management of HPV positives as part of cervical screening. An isothermal amplification HPV extended genotyping test (ScreenFire HPV RS assay) can assay up to 96 samples/controls in 1 hour plus preparation time. A novel format with pre-aliquoted reagents and an anti-contamination component (Zebra BioDome) could...
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