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Quorum quenching effects of linoleic and stearic acids on outer membrane vesicle-mediated virulence in Chromobacterium violaceum

27 Dec 2024

Abstract excerpt

Chromobacterium violaceum is a pathogenic bacterium that can infect humans and animals, yet the role of its outer membrane vesicles (OMVs) in mediating pathogenicity remains underexplored. This study evaluated the effects of linoleic acid (LA) and stearic acid (SA) on quorum sensing (QS)-mediated violacein production, biofilm formation, and OMV biogenesis in C. violaceum. Our findings revealed that 2 mM LA and 1...

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PMID: 39726991
DOI: 10.1080/08927014.2024.2446930

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