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Article

Clinical Outcomes of Early Phenotype-Desirable Antimicrobial Therapy for Enterobacterales Bacteremia.

JAMA network open - 2 Dec 2024

Moon Rena C, MacVane Shawn H, David Joy, Morton Jacob B, Rosenthal Ning, Claeys Kimberly C

Abstract excerpt

Importance: Initiating effective therapy early is associated with improved survival among patients hospitalized with gram-negative bloodstream infections; furthermore, providing early phenotype-desirable antimicrobial therapy (PDAT; defined as receipt of a β-lactam antibiotic with the narrowest spectrum of activity to effectively treat the pathogen's phenotype) is crucial for antimicrobial stewardship. However,...

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Identifiers

PMID: 39714841
DOI: 10.1001/jamanetworkopen.2024.51633
PMCID: PMC11667351

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