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Effects of Amino Acid Mutation in Cytochrome P450 (CYP96A146) of Descurainia sophia on the Metabolism and Resistance to Tribenuron-Methyl.

Journal of agricultural and food chemistry - 8 Jan 2025

Shen Jing, Yang Qian, Xu Fan, Han Yuxin, Li Yubin, Zheng Mingqi

Abstract excerpt

Cytochrome P450 monooxygenases (P450s) play important roles in herbicide resistance. In this study, there are four amino acid mutations (F39Y, H163Y, S203A, and V361E) between CYP96A146-S and CYP96A146-R, which were cloned, respectively, from susceptible (S) and tribenuron-methyl-resistant (TR) Descurainia sophia. The Arabidopsis expressing CYP96A146-S or CYP96A146-R showed resistance to tribenuron-methyl,...

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PMID: 39698796
DOI: 10.1021/acs.jafc.4c10217

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