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Identification of Functional Variants Between Tong Sheep and Hu Sheep by Whole-Genome Sequencing Pools of Individuals.

International journal of molecular sciences - 30 Nov 2024

Tang Xiaoqin, Wang Shuhui, Yi Xiaohua, Li Qi, Sun Xiuzhu

Abstract excerpt

Tong sheep, known for their superior meat quality and disease resilience, face breeding challenges due to low prolificacy, unlike Hu sheep, which exhibit higher fertility and growth rates. This study identified over 700,000 genetic variants between these breeds through pooled whole-genome sequencing. Functional analysis reveals key differences in pathways related to fat metabolism, insulin signaling, and cell...

Topics

Animals
Whole Genome Sequencing
Sheep
MicroRNAs
Polymorphism, Single Nucleotide
Breeding
Genetic Variation
Mutation
Phenotype

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39684630
DOI: 10.3390/ijms252312919
PMCID: PMC11641353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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