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ALG13-Related Epilepsy: Current Insights and Future Research Directions.

Neurochemical research - 14 Dec 2024

Gao Peng, Chen Haoran, Sun Yangyang, Qian Xin, Sun Tao, Fan Yuhan, Zhang Jing

Abstract excerpt

The ALG13 gene encodes a subunit of the uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transferase enzyme, which plays a key role in the N-linked glycosylation pathway. This pathway involves the attachment of carbohydrate structures to asparagine (Asn) residues in proteins within the endoplasmic reticulum, by which N-glycosylated proteins produced participate a wide range of processes such as electrical...

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PMID: 39673593
DOI: 10.1007/s11064-024-04300-y

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