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Article

Emergence of mcr-8.1-bearing MDR-hypervirulent Klebsiella pneumoniae ST307.

Microbiology spectrum - 4 Feb 2025

Sheng Jie, Cave Rory, Ter-Stepanyan Mary M, Lu Siyu, Wang Yingxiong, Liu Taihang, Mkrtchyan Hermine V

Abstract excerpt

We report for the first time whole-genome sequencing of four multidrug-resistant sequence type (ST) 307 Klebsiella pneumoniae recovered from patients in two hospitals in Armenia. Comparative genomic analysis revealed that the isolates were closely related, with a maximum of 39 single nucleotide polymorphism (SNP) differences in the core genome. All Armenian isolates carried the integrative and conjugative element...

Read the complete abstract on PubMed

Topics

Klebsiella pneumoniae
Drug Resistance, Multiple, Bacterial
Anti-Bacterial Agents
Humans
Klebsiella Infections
Microbial Sensitivity Tests

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Whole Genome Sequencing

Genome, Bacterial

Bacterial Proteins

Polymorphism, Single Nucleotide

Virulence

beta-Lactamases

Virulence Factors

Plasmids

Source

Open in PubMed Open full text

Identifiers

PMID: 39670759
DOI: 10.1128/spectrum.01910-24
PMCID: PMC11792491

Provenance

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