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Evaluation of VP4-VP2 sequencing for molecular typing of human enteroviruses

10 Dec 2024

Abstract excerpt

Enteroviruses and rhinoviruses are highly diverse, with over 300 identified types. Reverse transcription-polymerase chain reaction (RT-PCR) assays targeting their VP1, VP4, and partial VP2 (VP4-pVP2) genomic regions are used for detection and identification. The VP4-pVP2 region is particularly sensitive to RT-PCR detection, making it efficient for clinical specimen analysis. However, a standard type...

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PMID: 39656727
DOI: 10.1371/journal.pone.0311806

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