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Decoding the Ferroptosis-Related Gene Signatures and Immune Infiltration Patterns in Ovarian Cancer: Bioinformatic Prediction Integrated with Experimental Validation

1 Dec 2024

Abstract excerpt

Background: Ovarian cancer is a type of gynecological cancer with extremely high fatality rate. Ferroptosis, an iron-dependent regulated cell death, inhibits the immune infiltration of tumor cells. Therefore, it is worthwhile to explore the effects of ferroptosis-related gene signatures and immune infiltration patterns on the clinical prognosis of ovarian cancer. Methods: In this study, we used the mRNA...

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Cancer-related molecular mechanisms research
Ferroptosis and cancer prognosis
Immune cells in cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39654865
DOI: 10.2147/jir.s498740

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