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Article

Phenotypic subtypes of Xia-Gibbs syndrome: a latent class analysis.

European journal of human genetics : EJHG - 1 Dec 2025

Jiang Nan, Zhang Liyuan, Zheng Zeyan, Du Hanze, Chen Shi, Pan Hui

Abstract excerpt

Xia-Gibbs syndrome (XGS) is a rare neurodevelopmental disorder with considerable clinical heterogeneity. To further characterize the syndrome's heterogeneity, we applied latent class analysis (LCA) on reported cases to identify phenotypic subtypes. By searching PubMed, Embase, China National Knowledge Infrastructure and Wanfang databases from inception to February 2024, we enrolled 97 cases with nonsense,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39648204
DOI: 10.1038/s41431-024-01754-0
PMCID: PMC12669642

Genes

AHDC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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