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Uncovering the arsenal of class II bacteriocins in salivarius streptococci

14 Nov 2024

Abstract excerpt

Facing the antibiotic resistance crisis, bacteriocins are considered as a promising alternative to treat bacterial infections. In the human commensal Streptococcus salivarius, the production of unmodified bacteriocins (or salivaricins) is directly controlled at the transcriptional level by quorum-sensing. To discover hidden bacteriocins, we harnessed here the unique molecular signatures of salivaricins not yet...

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PMID: 39543239
DOI: 10.1038/s42003-024-07217-y

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