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Article

cGMP-dependent pathway and a GPCR kinase are required for photoresponse in the nematode Pristionchus pacificus.

PLoS genetics - 1 Nov 2024

Nakayama Kenichi, Hiraga Hirokuni, Manabe Aya, Chihara Takahiro, Okumura Misako

Abstract excerpt

Light sensing is a critical function in most organisms and is mediated by photoreceptor proteins and phototransduction. Although most nematodes lack eyes, some species exhibit phototaxis. In the nematode Caenorhabditis elegans, the unique photoreceptor protein Cel-LITE-1, its downstream G proteins, and cyclic GMP (cGMP)-dependent pathways are required for phototransduction. However, the mechanism of light-sensing...

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PMID: 39541254
DOI: 10.1371/journal.pgen.1011320
PMCID: PMC11563456

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