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Validation and next-generation update of a DNA methylation–based recurrence predictor for meningioma: A multicenter prospective study

6 Nov 2024

Abstract excerpt

BACKGROUND: We previously developed a DNA methylation-based risk predictor for meningioma, which has been used locally in a prospective fashion since its original publication. As a follow-up, we validate this model using a large prospective cohort and introduce a streamlined next-generation predictor compatible with newer methylation arrays. METHODS: Genome-wide methylation profiles were generated with the...

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PMID: 39503370
DOI: 10.1093/neuonc/noae236

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