Retinal microvascular phenotypes can track small vessel disease burden and CPAP treatment effectiveness in obstructive sleep apnea.

doi:10.1177/0271678X241291958

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Article

Retinal microvascular phenotypes can track small vessel disease burden and CPAP treatment effectiveness in obstructive sleep apnea.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Apr 2025

Giarratano Ylenia, Hill Elizabeth A, Hamid Charlene, Wiseman Stewart, Gray Calum, Chappell Francesca M, Coello Roberto Duarte, Valdés-Hernández Maria C, Ballerini Lucia, Stringer Michael S, Thrippleton Michael J, Jaime Garcia Daniela, Liu Xiaodi, Hewins William, Cheng Yajun, Black Sandra E, Lim Andrew, Sommer Rosa, Ramirez Joel, MacIntosh Bradley J, Brown Rosalind, Doubal Fergus, MacGillivray Tom, Wardlaw Joanna M, Riha Renata, Bernabeu Miguel O

Abstract excerpt

Optical coherence tomography angiography (OCT-A) retinal imaging enables in vivo visualization of the retinal microvasculature that is developmentally related to the brain and can offer insight on cerebrovascular health. We investigated retinal phenotypes and neuroimaging markers of small vessel disease (SVD) in individuals with obstructive sleep apnoea (OSA). We enrolled 44 participants (mean age 50.1 ± SD 9.1...

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Topics

Humans
Continuous Positive Airway Pressure

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Middle Aged

Female

Sleep Apnea, Obstructive

Retinal Vessels

Tomography, Optical Coherence

Phenotype

Adult

Microvessels

Source

Open in PubMed Open full text

Identifiers

PMID: 39487754
DOI: 10.1177/0271678X241291958
PMCID: PMC11563513

Genes

CPAP

Provenance

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