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Isolation and characterization of a novel S-gene mutation porcine deltacoronavirus with high pathogenicity from diarrhea piglet in Zhejiang Province, China, 2022.

Microbial pathogenesis - 1 Dec 2024

Xu Xiangwen, Sun Jing, Zheng Huihua, Du Xiaoxu, Wang Yutao, Cheng Jiongze, Liu Yijia, Ying Jiale, Zhao Yulin, Wang Ziqi, Yan Junfang, Duan Xing, Yang Yongchun, Ye Zhihui, Sun Dongbo, Song Houhui, Su Mingjun

Abstract excerpt

Porcine deltacoronavirus (PDCoV) is a coronavirus that causes diarrhea in suckling piglets and has the potential for cross-species transmission. Monitoring PDCoV evolution and identifying potential vaccine candidates are crucial due to its high mutation rates in pig populations. In this study, a Chinese PDCoV strain named ZD2022 was successfully isolated from diarrhea piglets in Zhejiang province, followed by...

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PMID: 39486553
DOI: 10.1016/j.micpath.2024.107095

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