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The role of gene mutations and immune responses in sensorineural hearing loss.

International immunopharmacology - 25 Dec 2024

Zhang Xu, Wu Junyi, Wang Maohua, Chen Li, Wang Peng, Jiang Qiao, Yang Chunping

Abstract excerpt

Sensorineural hearing loss (SNHL) is a prevalent clinical condition primarily attributed to dysfunction within various components of the auditory pathway, spanning from the inner ear to the auditory cortex. Recent research has illuminated immune and inflammation-mediated disorders of the inner ear as critical contributors to SNHL. Disruptions in the equilibrium of inflammatory mediators, chemokines, the...

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PMID: 39486181
DOI: 10.1016/j.intimp.2024.113515

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