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Article

Parental-effect gene-drive elements under partial selfing, or why do Caenorhabditis genomes have hyperdivergent regions?

Genetics - 8 Jan 2025

Rockman Matthew V

Abstract excerpt

Self-fertile Caenorhabditis nematodes carry a surprising number of Medea elements, alleles that act in heterozygous mothers and cause death or developmental delay in offspring that do not inherit them. At some loci, both alleles in a cross operate as independent Medeas, affecting all the homozygous progeny of a selfing heterozygote. The genomic coincidence of Medea elements and ancient, deeply coalescing...

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Identifiers

PMID: 39475455
DOI: 10.1093/genetics/iyae175
PMCID: PMC11708918

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