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Proteomic and serological markers for diagnosing cardia gastric cancer and precursor lesions in a Chinese population

25 Oct 2024

Abstract excerpt

Cardia gastric cancer (CGC) is prevalent in East Asia, and noninvasive, cost-effective screening methods are needed. This study investigated the diagnostic value of serum pepsinogen (PG), gastrin-17 (G-17), Helicobacter pylori (H. pylori) antibodies, and proteomic profiling for CGC and precancerous lesions. We conducted a case-control study involving biopsy-confirmed patients with CGC (n = 60), low-grade...

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PMID: 39455684
DOI: 10.1038/s41598-024-75912-1

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