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Article

Explainable 18F-FDG PET/CT radiomics model for predicting EGFR mutation status in lung adenocarcinoma: a two-center study.

Journal of cancer research and clinical oncology - 22 Oct 2024

Zuo Yan, Liu Qiufang, Li Nan, Li Panli, Fang Yichong, Bian Linjie, Zhang Jianping, Song Shaoli

Abstract excerpt

PURPOSE: To establish an explainable 18F-FDG PET/CT-derived prediction model to identify EGFR mutation status and subtypes (EGFR wild, EGFR-E19, and EGFR-E21) in lung adenocarcinoma (LUAD). METHODS: Baseline 18F-FDG PET/CT images of 478 patients with LUAD from 2 hospitals were collected. Data from hospital A (n = 390) was randomly split into a training group (n = 312) and an internal test group (n = 78), with...

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Identifiers

PMID: 39436414
DOI: 10.1007/s00432-024-05998-7
PMCID: PMC11496337

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