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Maternal periconception hyperglycemia, preconception diabetes, and risk of major congenital malformations in offspring

15 Oct 2024

Abstract excerpt

STUDY QUESTION: What are the roles of maternal preconception diabetes and related periconceptional hyperglycemia on the risk of major congenital malformations (MCMs) in offspring? SUMMARY ANSWER: Maternal periconceptional glycated hemoglobin (HbA1c) levels over 5.6% were associated with an increased risk of congenital heart defects (CHD) in the offspring, and maternal preconception diabetes was associated with an...

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PMID: 39406385
DOI: 10.1093/humrep/deae233

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