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Article

An automated commercial open access assay for detection of Mycoplasma genitalium macrolide resistance.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jan 2025

Lindroth Ylva, Hansson Lucia, Forslund Ola

Abstract excerpt

Azithromycin, a macrolide antibioticum, is the first-line treatment for Mycoplasma genitalium (MG), but resistant MG is an increasing problem. Macrolide resistance-mediated mutations (MRM) has been linked to point mutations in region V of the MG 23S rRNA gene. We have evaluated an open access analyzer (Panther Fusion, Hologic Inc) for detectability of MRM (mutations A2071G and A2072G) and MG wild type (WT) in...

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PMID: 39390913
DOI: 10.1111/apm.13477

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