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Development and validation of a prognostic model for colon cancer based on mitotic gene signatures and immune microenvironment analysis

9 Oct 2024

Abstract excerpt

BACKGROUND: Mitotic processes play a pivotal role in tumor progression and immune responses. However, the correlation between mitosis-related genes, clinical outcomes, and the tumor microenvironment (TME) in colon cancer remains unclear. This study aims to develop a prognostic and therapeutic significance model for colon cancer based on mitosis-related genes. METHODS: RNA expression profiles and clinical data of...

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PMID: 39382813
DOI: 10.1007/s12672-024-01421-2

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