Article
Unifying framework explaining how parental regulatory divergence can drive gene expression in hybrids and allopolyploids.
Nature communications - 8 Oct 2024
Janko Karel, Eisner Jan, Cigler Petr, Tichopád Tomáš
Abstract excerpt
Hybridization and polyploidy are powerful evolutionary forces, inducing a range of phenotypic outcomes, including non-additive expression, subgenome dominance, deviations in genomic dosage, and transcriptome downsizing. The reasons for these patterns and whether they are universal adaptive responses to genome merging and doubling remain debated. To address this, we develop a thermodynamic model of gene expression...
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