Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Construction of a novel model based on PVT1-MYC duet-related genes for predicting survival and characterization of the tumor microenvironment in pancreatic cancer.

Frontiers in immunology - 1 Jan 2024

Ren Bo, Ren Jie, Gu Minzhi, Liu Xiaohong, You Lei, Zhao Yupei

Abstract excerpt

Pancreatic cancer is an extremely malignant tumor. PVT1 and MYC signaling has been considered as a therapeutic target recently. Nonetheless, the prognostic values and critical regulatory networks of PVT1-MYC duet in pancreatic cancer remain unclear. Firstly, we identified PVT1-MYC duet-related genes using public databases. Then we analyzed our Hi-C and ChIP-seq data to confirm PVT1-MYC duet. We performed LASSO...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nomograms

Share to Pancreatic Neoplasms

Share to Prognosis

Share to Proto-Oncogene Proteins c-myc

Share to RNA, Long Noncoding

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 39376555
DOI: 10.3389/fimmu.2024.1435593
PMCID: PMC11456451

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Construction of a novel model based on PVT1-MYC duet-related genes for predicting survival and characterization of the tumor microenvironment in pancreatic cancer.PMID 39376555Read ↗

Infection with COVID-19 promotes the progression of pancreatic cancer through the PI3K-AKT signaling pathwaySemantic proximity Read ↗

Identification of stromal microenvironment characteristics and key molecular mining in pancreatic cancerSemantic proximity Read ↗

Establishment of a Prognostic Prediction System Based on Tumor Microenvironment of Pancreatic CancerSemantic proximity Read ↗

An Accurate Prognostic Model and Treatment for Pancreatic Carcinoma Based on the Tumor Immune MicroenvironmentSemantic proximity Read ↗

Integration of Single-Cell RNA Sequencing and Bulk RNA Sequencing Reveals That TAM2-Driven Genes Affect Immunotherapeutic Response and Prognosis in Pancreatic CancerSemantic proximity Read ↗

Identification and validation of a hypoxia-immune related prognostic signature for pancreatic cancerSemantic proximity Read ↗

Single-cell transcriptomics analysis reveals dynamic changes and prognostic signature in tumor microenvironment of PDACSemantic proximity Read ↗

A MyCAF-Based Signature for Prognosis, Immune Landscape, and Therapeutic Response in Pancreatic CancerSemantic proximity Read ↗

Comprehensive Analysis of Clinical Prognosis and Molecular Immune Characterization of TPM4 in Pancreatic CancerSemantic proximity Read ↗

Unraveling the role of Major Vault Protein as a novel immune-related biomarker that promotes the proliferation and migration in pancreatic adenocarcinomaSemantic proximity Read ↗

Prognostic Value of Drug Targets Predicted using Deep Bioinformatic Analysis of M6A-associated lncRNA-based Pancreatic Cancer Model Characteristics and its Tumour MicroenvironmentSemantic proximity Read ↗

PUM1 is upregulated by DNA methylation to suppress antitumor immunity and results in poor prognosis in pancreatic cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.