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The clinical application of metagenomic next-generation sequencing in immunocompromised patients with severe respiratory infections in the ICU

5 Oct 2024

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BACKGROUND: Early targeted antibiotic therapy is crucial for improving the prognosis of immunocompromised patients with severe respiratory infections (SRIs) in the intensive care unit (ICU). Metagenomic next-generation sequencing (mNGS) has shown significant value in pathogen detection, but research on lower respiratory tract microorganisms remains limited. METHODS: This study enrolled 234 patients with SRIs in...

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PMID: 39369191
DOI: 10.1186/s12931-024-02991-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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