Article
Placental extracellular vesicles promote cardiomyocyte maturation and fetal heart development
3 Oct 2024
Abstract excerpt
Congenital heart defects are leading causes of neonatal mortality and are often associated with placental abnormalities, but mechanisms linking placenta and heart development are poorly understood. Herein, we investigated a potential signaling network connecting the placenta and nascent heart in mice. We found that fetal hearts exposed to media conditioned by placental tissue or differentiated wild-type...
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