Article
A preliminary indication that HLA-A*03:01 may be associated with visceral leishmaniasis development in people living with HIV in Ethiopia.
PLoS neglected tropical diseases - 1 Sept 2024
de Vrij Nicky, Vandoren Romi, Ramadan Kadrie, Van Hul Anke, Ceulemans Ann, Kassa Mekibib, Melkamu Roma, Yeshanew Arega, Bogale Tadfe, Beyene Hailemariam, Sisay Kasaye, Kibret Aderajew, Mersha Dagnew, Cuypers Wim L, Vogt Florian, van Henten Saskia, Ritmeijer Koert, Pham Thao-Thy, Meysman Pieter, Laukens Kris, Cuypers Bart, Diro Ermias, Mohammed Rezika, van Griensven Johan, Adriaensen Wim
Abstract excerpt
Human immunodeficiency virus (HIV) co-infection is a major challenge for visceral leishmaniasis (VL) control, particularly in Ethiopia where the incidence of both pathogens is high. VL-HIV often leads to high rates of antileishmanial treatment failure and recurrent VL disease relapses. Considering the high prevalence of HIV and Leishmania in the Ethiopian population, preventing the progression of asymptomatic...
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