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Article

Molecular Epidemiology of Hepatitis D Virus in the North-East Region of Romania.

Pathogens (Basel, Switzerland) - 13 Sept 2024

Grecu Laura Iulia, Pavel-Tanasa Mariana, Matei Lilia, Sultana Camelia, Ruta Simona Maria, Grecu Razvan Ioan, Ursu Ramona Gabriela, Cianga Petru, Iancu Luminita Smaranda

Abstract excerpt

The hepatitis D virus (HDV) superinfection of individuals with chronic hepatitis B virus (HBV) infection causes severe liver damage and the poorest long-term prognosis among viral hepatitis. This is attributed to the unique pathogenic mechanisms of HDV characterized by a direct cytopathic effect on hepatocytes and a significant impairment of the host immune response. The HDV genotype largely influences the extent...

Read the complete abstract on PubMed

Topics

Humans
Romania
Hepatitis Delta Virus
Molecular Epidemiology
Male
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Hepatitis D

Phylogeny

Adult

Middle Aged

Genotype

Aged

Young Adult

RNA, Viral

Source

Open in PubMed Open full text

Identifiers

PMID: 39338984
DOI: 10.3390/pathogens13090793
PMCID: PMC11435033

Provenance

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