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Article

Genotype Characterization and MiRNA Expression Profiling in Usher Syndrome Cell Lines.

International journal of molecular sciences - 17 Sept 2024

Tom Wesley A, Chandel Dinesh S, Jiang Chao, Krzyzanowski Gary, Fernando Nirmalee, Olou Appolinaire, Fernando M Rohan

Abstract excerpt

Usher syndrome (USH) is an inherited disorder characterized by sensorineural hearing loss (SNHL), retinitis pigmentosa (RP)-related vision loss, and vestibular dysfunction. USH presents itself as three distinct clinical types, 1, 2, and 3, with no biomarker for early detection. This study aimed to explore whether microRNA (miRNA) expression in USH cell lines is dysregulated compared to the miRNA expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39337481
DOI: 10.3390/ijms25189993
PMCID: PMC11432263

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