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Article

The Impact of the G6PD Gene Mutations in Patients with Chronic Hepatitis C Infection Treated with Direct-Acting Antivirals: A Multicenter Observational Study.

Genes - 24 Aug 2024

Smirne Carlo, Crobu Maria Grazia, Gerevini Chiara, Berton Alessandro Maria, Rapetti Rachele, Pasini Barbara, Ravanini Paolo, Pirisi Mario

Abstract excerpt

Following the advent of direct-acting antivirals (DAAs), the treatment of hepatitis C virus (HCV) infection is now rarely challenging. However, data are still limited concerning DAA use in patients affected by glucose-6-phosphate dehydrogenase deficiency (G6PDd). Based on these considerations, the goal of this study was to evaluate the effectiveness and safety of DAAs in this subpopulation. A retrospective...

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Identifiers

PMID: 39336707
DOI: 10.3390/genes15091116
PMCID: PMC11431558

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