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RPS6KA1 is a histone acetylation-related oncoprotein in acute myeloid leukemia which is targeted by afzelin

27 Sept 2024

Abstract excerpt

BACKGROUND: Histone acetylation plays a critical role in the progression of acute myeloid leukemia (AML). This study aimed to explore the prognostic significance and biological implications of histone acetylation-related genes in AML and to identify potential oncoproteins and therapeutic compounds. METHODS: Genes associated with AML and histone acetylation were identified using the TCGA-LAML and IMEx Interactome...

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Share to Acute Myeloid Leukemia Research
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PMID: 39333927
DOI: 10.1186/s12885-024-12886-3

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