Integrative metagenomic and lipidomic analyses reveal alterations in children with obesity and after lifestyle intervention

Abstract excerpt

Background Despite emerging evidence linking alterations in gut microbiota to childhood obesity, the metabolic mechanisms linking gut microbiota to the lipid profile during childhood obesity and weight loss remain poorly understood. Methodology In this study, children with obesity were treated with lifestyle weight loss therapy. Metagenomics association studies and serum untargeted lipidomics analyses were...

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