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Evaluation of the GenoType NTM-DR line probe assay for nontuberculous mycobacteria using whole genome sequences as reference standard.

Diagnostic microbiology and infectious disease - 1 Dec 2024

Epperson L Elaine, Davidson Rebecca M, Kammlade Sara M, Hasan Nabeeh A, Nick Sophie E, Machado Iara M P, Rodriguez Valerie H, Appleman Aaron, Helstrom Niels K, Strong Michael

Abstract excerpt

Pulmonary nontuberculous mycobacteria (NTM) disease is an emerging public health challenge that is especially problematic in people with cystic fibrosis (CF). Effective treatment depends on accurate species and subspecies identification and antimicrobial susceptibility status. We evaluated the GenoType NTM-DR VER 1.0 assay using biobanked NTM isolates with whole genome sequence (WGS) data and control isolates...

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PMID: 39293318
DOI: 10.1016/j.diagmicrobio.2024.116526

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