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Comparison of targeted next-generation sequencing and traditional microbial culture in the diagnosis of pulmonary infections

10 Sept 2024

Abstract excerpt

This study investigated the diagnostic potential of targeted next-generation sequencing (tNGS) for pulmonary infections. The positivity rate of tNGS was significantly higher than that of traditional microbial culture (92.6 % vs 25.2 %, χ2 = 378.272, P < 0.001). The proportion of two or more species of pathogens detected using tNGS exceeded that detected using microbial culture (χ2 = 337.283, P < 0.001). There...

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PMID: 39276718
DOI: 10.1016/j.diagmicrobio.2024.116534

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