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Primary succession of Bifidobacteria drives pathogen resistance in neonatal microbiota assembly

6 Sept 2024

Abstract excerpt

Human microbiota assembly commences at birth, seeded by both maternal and environmental microorganisms. Ecological theory postulates that primary colonizers dictate microbial community assembly outcomes, yet such microbial priority effects in the human gut remain underexplored. Here using longitudinal faecal metagenomics, we characterized neonatal microbiota assembly for a cohort of 1,288 neonates from the UK. We...

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PMID: 39242817
DOI: 10.1038/s41564-024-01804-9

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