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Isolation and characterization of genetic variants of Orthohantavirus hantanense from clinical cases of HFRS in Jiangxi Province, China.

PLoS neglected tropical diseases - 1 Sept 2024

Liu Shiwen, Deng Zhishi, Li Jianxiong, Zou Long, Sun Xiuhui, Liu Xiaoqing, Shi Yong, Huang Shunqiang, Wu Yangbowen, Lei Jinhui, Liu Peipei, Zhang Pei, Xiong Ying, Long Zhong-Er

Abstract excerpt

BACKGROUND: Hemorrhagic fever with renal syndrome (HFRS) is a severe public health problem in Jiangxi province, China. Previous studies reported genetic variants of Orthohantavirus hantanense (Hantaan virus, HTNV) in rodents in this area. However, the relationship between HTNV variants and human infection needs to be confirmed. This study aimed to identify the HTNV variants in patients and to understand the...

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PMID: 39235995
DOI: 10.1371/journal.pntd.0012439
PMCID: PMC11376573

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